In this guide
Prediction markets focused on science and technology draw participation from highly specialised individuals — academics, technologists, and science communicators who can interpret technical breakthroughs with greater speed than mainstream market participants. These venues reward specialised knowledge and rigorous analysis.
Active Science & Technology Prediction Markets (2026)
Space Exploration
- SpaceX Starship reaches orbit with payload: ~72-78%
- Artemis Moon landing in 2026: ~35-42%
- SpaceX Mars mission launch before 2030: ~55-62%
- Commercial space station operational in 2026: ~28-34%
Artificial Intelligence
- AGI claimed by major lab before 2028: ~22-28%
- AI system passes ARC-AGI benchmark (100%): ~38-44%
- EU AI Act High-Risk classification of LLMs: ~62-68%
Biotechnology & Medicine
- CRISPR gene therapy approved for new indication in US: ~65-72%
- GLP-1 drug market exceeds $150B annual revenue: ~55-62%
- Alzheimer's treatment showing 50%+ disease modification: ~28-34%
Clean Energy
- Nuclear fusion net energy gain sustained for 60+ seconds: ~35-42%
- Global solar capacity exceeds 5 TW: ~65-70%
- Solid-state battery in commercial EV by major automaker: ~38-44%
Edge Sources in Science/Tech Markets
- Preprint servers (arXiv, bioRxiv): emerging research findings made public prior to formal peer evaluation
- Patent filings: technological breakthroughs frequently signal patent submissions weeks or months earlier
- Regulatory pipeline: FDA, EMA approval schedules for pharmaceutical and biomedical innovations
- Engineering conference presentations: SpaceX, NASA, and technology sector strategic direction and timelines
FAQ
- How do science prediction markets resolve?
- These markets depend on verifiable public information: company announcements, published research in peer-reviewed journals, official government regulatory decisions, or established news organisations (AP, Reuters).
- Are there niche science markets not listed on PolyGram?
- PolyGram features prominent science markets. For specialised or obscure topics, Manifold Markets (using play currency) provides a broader range of user-generated markets.
- Do researchers trade prediction markets about their own field?
- Absolutely — and they typically possess the strongest informational advantage. Professional consensus within research communities (evident at academic gatherings) frequently moves ahead of market valuations by several weeks.